| Autor: |
Ribeiro, Margarida, O'Neill, João Goyri, Maurício, J. Cruz |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Popis: |
Purpose: The thinning of the corpus callosum (CC) is a sign of brain changes related to age. The use of quantitative methods can help to discriminate the pathological cerebral atrophy from the normal brain aging. This study aimed to quantify the atrophy of frontal lobe in subjects with the age recoded in [< 65 and ≥66] years old and to investigate its relationship with the dimensions (length and volume) of the CC. Methods and Materials: From T1w2D whole-brain sequence the length was assessed through the corpus callosum index (CCI). To assess the volume of CC the FreeSurfer package segmentation was used. The atrophy of frontal lobe was assessed by visual rating scale in the frontal cortex. To apply the atrophy rating scale, the relationship between sulcus and gyrus was assessed in coronal T1w images by two experts using 5 points Likert scale. All subjects were undergoing a 1.5T MRI INTERA scanner (Philips Medical, Systems Best, Netherlands) performing 96 valid cases. info:eu-repo/semantics/publishedVersion |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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