Sémiologie et pronostic de l’infection congénitale à cytomégalovirus après primo-infection maternelle du second trimestre de la grossesse
| Autor: | Cornet, Nathalie |
|---|---|
| Přispěvatelé: | Université Paris Descartes - Paris 5 (UPD5), Yves Ville |
| Jazyk: | francouzština |
| Rok vydání: | 2019 |
| Předmět: |
Diagnostic Imaging
MESH: Cytomegalovirus Small For Gestational Age Infection congénitale MESH: Infant small for gestational age Congenital Infection Pronostic Cytomegalovirus Petit poids pour l’âge gestationnel MESH: Toxoplasmosis Congenital Imagerie anténatale MESH: Prognosis [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Médecine humaine et pathologie. 2019 |
| Popis: | Congenital CMV is a major cause of neurological and sensory impairment in children. Objective - Description of the symptomatology and radiological semiology of infected fetuses in the second trimester of pregnancy; assessment of the prevalence and neonatal and long-term prognosis of fetuses with intrauterine growth restriction (IUGR) and small for gestational age birth weight (SGA). Material and Method - Monocentric retrospective study including patients referred for CMV seroconversion in the second trimester of pregnancy with a positive CMV viral load in amniotic fluid and a known neonatal outcome. Results - 111 fetuses had positive amniocentesis for CMV, 33 of them after second trimester seroconversion (29.7%). 21.2% of the fetuses were symptomatic at birth but none were long-term symptomatic. Radiological semiology, essentially composed of extracerebral signs, was a prognostic factor for birth symptomatology in univariate analysis. In utero, fetuses with IUGR were significantly more symptomatic at birth than eutrophic fetuses (64.7% vs. 12.1%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|