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Mémoire de DES (Diplôme d'Etudes Spécialisées) tenant lieu de thèse d'exercice. Thèse proposée pour un prix de thèse.; Anti-Aspergillus IgG are important biomarkers for the diagnosis of chronic pulmonary aspergillosis (CPA) and allergic broncho-pulmonary aspergillosis (ABPA). This study aimed to compare a new EIA kit (Bordier affinity products) to the Bio-Rad and the Virion\Serion EIAs. Through a multicentric prospective study, 436 sera from 352 patients, including 136 CPA, 94 ABPA and 206 controls, were tested. The sensitivities and specificities were 97%, 90.3%; 91.7%, 91.3; and 86.1%, 81.5% for Bordier, Bio-Rad and Virion\Serion, respectively. A McNemar analysis confirmed the higher sensitivity of Bordier as compared to Bio-Rad (p |
