Understanding the complexity of glycaemic health:systematic bio-psychosocial modelling of fasting glucose in middle-age adults; a DynaHEALTH study

Autor: Lowry, E. (Estelle), Rautio, N. (Nina), Karhunen, V. (Ville), Miettunen, J. (Jouko), Ala-Mursula, L. (Leena), Auvinen, J. (Juha), Keinänen-Kiukaanniemi, S. (Sirkka), Puukka, K. (Katri), Prokopenko, I. (Inga), Herzig, K.-H. (Karl-Heinz), Lewin, A. (Alexandra), Sebert, S. (Sylvain), Järvelin, M.-R. (Marjo-Riitta)
Jazyk: angličtina
Rok vydání: 2019
Popis: Background: The prevention of the risk of type 2 diabetes (T2D) is complicated by multidimensional interplays between biological and psychosocial factors acting at the individual level. To address the challenge we took a systematic approach, to explore the bio-psychosocial predictors of blood glucose in mid-age. Methods: Based on the 31-year and 46-year follow-ups (5,078 participants, 43% male) of Northern Finland Birth Cohort 1966, we used a systematic strategy to select bio-psychosocial variables at 31 years to enable a data-driven approach. As selection criteria, the variable must be (i) a component of the metabolic syndrome or an indicator of psychosocial health using WHO guidelines, (ii) easily obtainable in general health check-ups and (iii) associated with fasting blood glucose at 46 years (P
Databáze: OpenAIRE