Autoimmune antibodies to collagen XIII in myasthenia gravis patients

Autor: Tu, H. (Hongmin), Pirskanen‐Matell, R. (Ritva), Heikkinen, A. (Anne), Oikarainen, T. (Tuomo), Risteli, J. (Juha), Pihlajaniemi, T. (Taina)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Popis: Introduction: Evaluation of the nerve fascicular structure can be useful in diagnosing nerve damage, but it is a very challenging task with 3T MRI because of limited resolution. In this pilot study, we present the feasibility of high‐resolution 7T MRI for examining the nerve fascicular structure. Methods: A 3‐dimensional (3D) gradient‐spoiled sequence was used for imaging peripheral nerves in extremities. Images acquired with different in‐plane resolutions (0.42 × 0.42 mm vs. 0.12 × 0.12 mm), and different main field strengths (7T vs. 3T) were compared. Results: The individual nerve fascicles were identified at 0.12 × 0.12 mm resolution in both field strengths but not at 0.42 × 0.42 mm resolution. The fascicular structure was more sharply depicted in 7T images than in 3T images. Discussion: High‐resolution 3D imaging with 7T MRI demonstrated feasibility for imaging nerve fascicular structures.
Databáze: OpenAIRE