| Autor: |
Kamakura, R. (Remi), Raza, G. S. (Ghulam Shere), Sodum, N. (Nalini), Lehto, V.-P. (Vesa-Pekka), Kovalainen, M. (Miia), Herzig, K.-H. (Karl-Heinz) |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Popis: |
Obesity is one of the major global threats to human health and risk factors for cardiometabolic diseases and certain cancers. Glucagon-like peptide-1 (GLP-1) plays a major role in appetite and glucose homeostasis and recently the USFDA approved GLP-1 agonists for the treatment of obesity and type 2 diabetes. GLP-1 is secreted from enteroendocrine L-cells in the distal part of the gastrointestinal (GI) tract in response to nutrient ingestion. Endogenously released GLP-1 has a very short half-life of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
