Evaluation of the measurement of hemoglobin by the Hemocue System (R) in the preterm neonate less than 28 days old

Autor: Barcat, L., Dekens, C., Caron-Lesenechal, E., Degorre, C., Cauliez, A., Riou, B., Vasseur, A., Gromada, V., Leke, André, Bach, Véronique, Tourneux, Pierre
Přispěvatelé: CHU Amiens-Picardie, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Périnatalité et Risques Toxiques - UMR INERIS_I 1 (PERITOX), Institut National de l'Environnement Industriel et des Risques (INERIS)-Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Archives de Pédiatrie
Archives de Pédiatrie, 2016, 23 (3), pp.255-260. ⟨10.1016/j.arcped.2015.12.003⟩
ISSN: 0929-693X
1769-664X
DOI: 10.1016/j.arcped.2015.12.003⟩
Popis: International audience; Background. Hemoglobin (Hb) measurement is essential for the monitoring of anemia in preterm neonates to assess if any bleeding (pulmonary, cerebral, digestive) is present. EDTA samples require 500 mu L vs. 10 mu L for the Hemocue (R) system. This system has been evaluated and validated in adults and children but not in preterm neonates with fetal hemoglobin. The aim of the study was to compare Hb measurement with the Hemocue (R) system vs. the EDTA laboratory system on fetal Hb in preterm neonates. Materials and methods. This was a prospective study conducted in the preterm intensive care unit in the Amiens Hospital. Preterm neonates, before 28 days of life, requiring EDTA (Hb) measurement were included. Two Hemocues (R) were performed at the same time. Postnatal age (correlated to the fetal hemoglobin level decrease), blood sample site, and other factors that could influence the Hb result were evaluated. Results. Seventy-six EDTA and 152 Hemocue (R) samples from 38 preterm neonates were included. The term was 28.1 +/- 3.7 weeks of gestation, the birth weight was 1215.5 +/- 657 g. We found a good correlation between the Hemocue (R) and EDTA samples (Hemocue (R) = EDTA*0.94 - 0.4; R-2 = 0.63; P < 0.001). The influence of confounding factors was insignificant. Conclusion. The use of the Hemocue (R) system showed a good correlation with the EDTA measurement of fetal Hb, with a moderate bias (-0.2 +/- 1.5 g/dL), which remained stable for the first 28 days of life. (C) 2015 Elsevier Masson SAS. All rights reserved.
Databáze: OpenAIRE
Externí odkaz: