| Popis: |
The main theme of this bachelor thesis is a quality control of blood products which are prepared in the Transfusion Centre in the České Budějovice Hospital. In my thesis, I focus on the rudimentary blood products manufactured from whole blood. These include resuspended erythrocytes without a buffy coat (EBR), plasma (P), mixed thrombocytes without leukocytes from a buffy coat in a spare solution (TBSDR) and mixed thrombocytes without leukocytes (TBSD). The aim of this work is a statistical analysis of quality of the aforementioned blood products used in the past 5 years. Moreover, I have devised my own quality control of the newest blood products TBSDR. The theoretical part addresses blood donors´ control, methods of blood collection, blood processing and procedures which may significantly influence the quality of blood products. I also describe the examined blood products and the quality control process. In the practical part, I deal with the procedure of examining the particular parameters of blood products´ quality control and their assessment. After the preparation of blood products, sampling is done as well as the control of both efficient and undesirable components (erythrocytes, leukocytes, thrombocytes, hemoglobin, hematocrit). Assessment of stability and sterility of blood products (hemolysis, pH, coagulation factors) is done at the end of their expiration. I will focus more carefully on the TBSDR blood product quality control which starts one month after the blood product is implemented into a production process and which lasts six months. Statistical control of the process is applied during the quality control. In the past 5 years, the quality of blood products has been satisfactory. The newly implemented blood product TBSDR is more high-quality than the previous TBDS. TBSDR provides not only patients but also transfusion centers with many advantages. |
