Methods of molecular cytogenetics: evolution, analysis, comparison
| Autor: | Budková, Kateřina |
|---|---|
| Přispěvatelé: | Šolc, Roman, Daňková, Pavlína |
| Jazyk: | čeština |
| Rok vydání: | 2016 |
| Předmět: |
polymerázová řetězová reakce
pruhování chromosomů comparative genomic hybridization oncocytogenetics fluorescenční in situ hybridizace metody molekulární cytogenetiky onkocytogenetika methods od molecular cytogenetics komparativní genomová hybridizace fluorescent in situ hybridization polymerase chain reaction multiplex ligation-dependent probe amplification chromosome banding |
| Popis: | Cytogenetics is a branch of genetics that is concerned with the study of the structure and function of chromosomes, especially during the cell division. Chromosomal abnormalities that may occur during this process are often associated with the emergence of various diseases. Cytogenetic methods are primarily used to detect these abnormalities. Traditional methods allow resolution at the level of whole chromosomes, the introduction of new molecular methods led to a significant refinement of these analyzes. Today's methods allow easy analysis of chromosomes to the level of individual sequences. Despite significant differences between classical and modern cytogenetic techniques, classical cytogenetic methods are not evil, but they are still widely used. Combining classical and molecular methods in order to obtain a comprehensive analysis of chromosomal rearrangements is no exception. |
| Databáze: | OpenAIRE |
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