Conformationally constrained adamantaneoxazolines of pharmacological interest

Autor: Papanastasiou, I. Foscolos, G.B. Tsotinis, A. Oláh, J. Ovádi, J. Radhika Prathalingam, S. Kelly, J.M.
Jazyk: angličtina
Rok vydání: 2008
Popis: New conformationally constrained adamantane 2-oxazoline building blocks 1-4 were synthesized and their antimicrotubule and antitrypanosomal potency was investigated. Although most of the new compounds affect tubulin polymerization, this does not make a major contribution to trypanocidal activity. © 2008 The Japan Institute of Heterocyclic Chemistry.
Databáze: OpenAIRE