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Background and study aims The diagnosis of cholangiocarcinoma (CCA) is difficult. The present study aimed to assess the clinical features, diagnosis, and survival in CCA. Patients and methods This is a prospective study on 46 patients with CCA who underwent endoscopic retrograde cholangiopancreatography (ERCP) or surgical resection and 20 controls with a clinical and ERCP suspicion for CCA in whom surgical biopsy and/or 4-year follow-up showed a benign biliary stricture. Results The median age at presentation was 71 years (range 44–88). Thirty-four patients (73.9%) presented with painless jaundice. Median CA 19-9 value was 188 IU/L (range 1–49,138), with a level of |
