Increased hydrolysis of oximino-β-lactams by CMY-107, a Tyr199Cys mutant form of CMY-2 produced by Escherichia coli

Autor:	Kotsakis, S.D. Miriagou, V. Vetouli, E.E. Bozavoutoglou, E. Lebessi, E. Tzelepi, E. Tzouvelekis, L.S.
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	parasitic diseases chemical and pharmacologic phenomena bacterial infections and mycoses therapeutics complex mixtures
Popis:	The cephalosporinase CMY-107, a Tyr199Cys mutant form of CMY-2 encoded by an IncI self-transferable plasmid carried by an Escherichia coli clinical strain, was characterized. The enzyme hydrolyzed oximino-cephalosporins and aztreonam more efficiently than CMY-2 did. © 2015, American Society for Microbiology. All Rights Reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______2127::f08dc4fe05193b580a292984edc8635a https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3060711 Zobrazit plný text záznamu