Autor: |
Tsirigotis, P. Triantafyllou, K. Girkas, K. Giannopoulou, V. Ioannidou, E. Chondropoulos, S. Kalli, T. Papaxoinis, G. Pappa, V. Papageorgiou, E. Economopoulos, T. Ladas, S.D. Dervenoulas, J. |
Jazyk: |
angličtina |
Rok vydání: |
2008 |
Popis: |
Oral and/or intestinal mucositis is a severe complication of hematopoietic SCT. Keratinocyte growth factor (KGF) has proven activity in the prevention of oral mucositis. We examined the efficacy of KGF in the prevention of intestinal mucositis. From January 2006 until December 2007, 35 consecutive patients underwent autologous SCT (auto-SCT) in our institution. A total of 15 consecutive patients who underwent auto-SCT from March 2007 to December 2007 received KGF for the prevention of mucositis and were included in the study group A, whereas 20 consecutive patients treated from January 2006 to March 2007, were included in the historical control group B. Oral and intestinal mucositis were significantly less severe in group A (P = 0.002 and P |
Databáze: |
OpenAIRE |
Externí odkaz: |
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