| Autor: |
Michaelides, Andreas P. Tousoulis, Dimitrios Fourlas, Christos A. Vyssoulis, Gregory P. Andrikopoulos, George K. and Aznaouridis, Konstantinos A. Stefanadis, Christodoulos I. |
| Jazyk: |
angličtina |
| Rok vydání: |
2007 |
| Popis: |
Background: It has been previously postulated that Thallium-201 (Tl-201) scintigraphy is characterized by relatively low specificity in hypertensive patients. This study was undertaken to assess any possible influence of false-positive scintigraphic results on the prognosis of hypertensive patients. Methods: The study group comprised 179 consecutive hypertensive patients (128 men and 51 women), aged 50 7 years, who underwent exercise Tl-201 scintigraphy and coronary angiography (patients with normal scintigraphic results underwent coronary angiography due to persistent angina-like symptoms). All patients with normal coronary arteries underwent a second Tl-201 scintigraphy within 36 +/- 6 months. Patients with reversible ischemia in the second scintigraphy underwent also a second coronary angiography. Results: Coronary artery disease (CAD) was detected in 78 (44%) patients, while the rest 101 (56%) patients had normal coronary arteries. Abnormal scintigraphic results were revealed in 66 (85%) patients with CAD and in 38 (38%) patients without CAD. Twenty-two (58%) of the 38 hypertensive patients with false-positive scintigraphic results presented reversible ischemia of the infero-posterior wall of the left ventricle. Coronary artery disease was detected in 7 (32%) of these patients during the follow-up period. Conclusions: Hypertensive patients with normal coronary arteries and false-positive scintigraphic results usually present with reversible ischemia of the infero-posterior wall of the left ventricle. This group of patients seems to be at increased risk of developing CAD in a long-term follow-up period. (c) 2006 Elsevier Ireland Ltd. All rights reserved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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