Effectiveness of Transmitted Drug Resistance Testing before Initiation of Antiretroviral Therapy in HIV-Positive Individuals

Autor: Lodi, S. Günthard, H.F. Gill, J. Phillips, A.N. Dunn, D. Vu, Q. Siemieniuk, R. Garcia, F. Logan, R. Jose, S. Bucher, H.C. Scherrer, A.U. Reiss, P. Van Sighem, A. Boender, T.S. Porter, K. Gilson, R. Paraskevis, D. Simeon, M. Vourli, G. Moreno, S. Jarrin, I. Sabin, C. Hernán, M.A.
Jazyk: angličtina
Rok vydání: 2019
Popis: Background:For people living with HIV, major guidelines in high-income countries recommend testing for transmitted drug resistance (TDR) to guide the choice of first-line antiretroviral therapy (ART). However, individuals who fail a first-line regimen can now be switched to one of several effective regimens. Therefore, the virological and clinical benefit of TDR testing needs to be evaluated.Methods:We included individuals from the HIV-CAUSAL Collaboration who enrolled
Databáze: OpenAIRE