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In the present study the effect of an exercise rehabilitation program on exercise capacity and peripheral muscle oxygenation in patients with congestive heart failure (CHF) was evaluated. The population study consisted of 14 stable CHF patients that completed a rehabilitation program of 36 sessions. Eight patients were assigned to interval training (IT) that included alternations of 30 s of exercise with 60 s of rest, for 40 min per session [Meyer, K., Samek, L., Schwaibold, M., Westbrook, S., Hajric, R., Lehmann, M., et al. 1996. Physical responses to different modes of interval exercise in patients with chronic heart failure-application to exercise training. European Heart Journal 17, 1040-1047; Working group on cardiac rehabilitation and exercise physiology and working group on heart failure of the ESC, 2001. Recommendations for exercise training in chronic heart failure patients. European Heart Journal 22, 125-135], and six patients were assigned to IT for 20 min followed by strength training. Rehabilitation program resulted in a significant increase in exercise capacity as assessed by VO2peak (17 ± 5 vs 20 ± 6 ml/kg per min, p = 0.002). This result was accompanied by a significant decrease of the mean time constant (mtc) of the exponential curve that describes the rise of tissue oxygenation after a submaximal cardiopulmonary exercise test (CPET) (from 287 ± 90 to 217 ± 93 s, p = 0.02). Such improved oxygen kinetics may be the result of increased oxygen delivery to working skeletal muscle or/and improvement of muscle oxidative metabolism. In conclusion, exercise training improves exercise capacity and peripheral microcirculation in CHF patients. NIRS during recovery of submaximal CPET can provide easily measured oxygenation indices for assessment of the functional status of these patients' population. Relevance to industry. NIRS-derived indices are helpful in assessment of the influence of working activities upon functional status of healthy or diseased people under the particular conditions of the occupational environment. © 2009 Elsevier B.V. All rights reserved. |
