| Autor: |
Foteinogiannopoulou, Kalliopi Karmiris, Konstantinos Axiaris, Georgios Velegraki, Magdalini Gklavas, Antonios Kapizioni, Christina Karageorgos, Charalabos Kateri, Christina and Katsoula, Anastasia Kokkotis, Georgios Koureta, Evgenia and Lamouri, Charikleia Markopoulos, Panagiotis Palatianou, Maria and Pastras, Ploutarchos Fasoulas, Konstantinos Giouleme, Olga and Zampeli, Evanthia Theodoropoulou, Aggeliki Theocharis, Georgios Thomopoulos, Konstantinos Karatzas, Pantelis and Katsanos, Konstantinos H. Kapsoritakis, Andreas Kourikou, Anastasia Mathou, Nikoleta Manolakopoulos, Spilios and Michalopoulos, Georgios Michopoulos, Spyridon Boubonaris, Alexandros Bamias, Giorgos Papadopoulos, Vasileios and Papatheodoridis, George Papaconstantinou, Ioannis Pachiadakis, Ioannis Soufleris, Konstantinos Tzouvala, Maria Triantos, Christos Tsironi, Eftychia Christodoulou, Dimitrios K. and Koutroubakis, Ioannis E. Hellenic Grp Study IBD |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Popis: |
Background: Anemia is a common extraintestinal manifestation of Inflammatory Bowel Disease (IBD) affecting negatively the patients’ quality of life. The aim of this study was to determine the frequency and real-life management of anemia in IBD patients in Greece. Methods: This study was conducted in 17 Greek IBD referral centers. Demographic, clinical, laboratory, IBD and anemia treatment data were collected and analyzed retrospectively. Results: A total of 1394 IBD patients [560 ulcerative colitis (UC), 834 Crohn’s disease (CD)] were enrolled. Anemia at any time was reported in 687 (49.3%) patients of whom 413 (29.6%) had episodic and 274 (19.7%) had recurrent/persistent anemia. Anemia was diagnosed before IBD in 45 (6.5%), along with IBD in 269 (39.2%) and after IBD in 373 (54.3%) patients. In the multivariate analysis the presence of extraintestinal manifestations (p = 0.0008), IBD duration (p = 0.026), IBD related surgeries and hospitalizations (p = 0.026 and p = 0.004 accordingly) were risk factors of recurrent/persistent anemia. Serum ferritin was measured in 839 (60.2%) IBD patients. Among anemic patients, 535 (77.9%) received treatment. Iron supplementation was administered in 485 (90.6%) patients, oral in 142 (29.3%) and intravenous in 393 (81%). Conclusions: The frequency of anemia in IBD patients, followed at Greek referral centers, is approximately 50%. Development of recurrent/persistent anemia may be observed in 20% of cases and is independently associated with the presence of extraintestinal manifestations, IBD duration, IBD related surgeries and hospitalizations. Anemia treatment is administered in up to [Formula: see text] of anemia IBD patients with the majority of them receiving iron intravenously. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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