| Autor: |
Nicolaidou, Polyxeni Stavrinadis, Ilias Loukou, Ioanna and Papadopoulou, Anna Georgouli, Helen Douros, Konstantinos and Priftis, Kostas N. Gourgiotis, Dimitrios Matsinos, Yiannis G. and Doudounakis, Stavros |
| Jazyk: |
angličtina |
| Rok vydání: |
2006 |
| Popis: |
Introductions: Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). Objectives: Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with CF. materials and methods: The statuses of vitamins K and D in relation to biochemical markers of bone metabolism and BMD were examined in 20 CF children receiving vitamin D supplements but not vitamin K supplements. Laboratory tests were carried out at the beginning of the study period and after 1 year of vitamin K supplementation (10 mg single oral dose/week) and the results were compared; the results were also compared with those of 25 healthy controls. Results and discussions: Ten of the CF patients had BMD z-score |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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