| Autor: |
Coulter, Ian C. Kulkarni, Abhaya V. Sgouros, Spyros and Constantini, Shlomi Constantini, Shlomi Sgouros, Spyros and Kulkarni, Abhaya V. Leitner, Yael Kestle, John R. W. and Cochrane, Douglas D. Choux, Maurice Gjerris, Fleming Sherer, Adina Akalan, Nejat Bilginer, Burcak Navarro, Ramon and Vujotic, Ljiljana Haberl, Hannes Thomale, Ulrich-Wilhelm and Zuccaro, Graciela Jaimovitch, Roberto Frim, David Loftis, Lori Swift, Dale M. Robertson, Brian Gargan, Lynn and Bognar, Laszlo Novak, Laszlo Cseke, Georgina Cama, Armando and Ravegnani, Giuseppe Marcello Preuss, Matthias Schroeder, Henry W. Fritsch, Michael Baldauf, Joerg Mandera, Marek and Luszawski, Jerzy Skorupka, Patrycja Mallucci, Conor and Williams, Dawn Zakrzewski, Krzysztof Nowoslawska, Emilia and Srivastava, Chhitij Mahapatra, Ashok K. Kumar, Raj Sahu, Rabi Narayan Melikian, Armen G. Korshunov, Anton Galstyan, Anna Suri, Ashish Gupta, Deepak Grotenhuis, J. Andre van Lindert, Erik J. da Costa Val, Jose Aloysio Di Rocco, Concezio and Tamburrini, Gianpiero Zymberg, Samuel Tau Cavalheiro, Sergio and Jie, Ma Feng, Jiang Friedman, Orna Rajmohamed, Naheeda and Roszkowski, Marcin Barszcz, Slawomir Jallo, George and Pincus, David W. Richter, Bridget Mehdorn, H. M. Schultka, Susan de Ribaupierre, Sandrine Thompson, Dominic Gatscher, Silvia Wagner, Wolfgang Koch, Dorothee Cipri, Saverio and Zaccone, Claudio McDonald, Patrick Int Infant Hydrocephalus Study |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Popis: |
Purpose The craniometrics of head circumference (HC) and ventricular size are part of the clinical assessment of infants with hydrocephalus and are often utilized in conjunction with other clinical and radiological parameters to determine the success of treatment. We aimed to assess the effect of endoscopic third ventriculostomy (ETV) and shunting on craniometric measurements during the follow-up of a cohort of infants with symptomatic triventricular hydrocephalus secondary to aqueductal stenosis. Methods We performed a post hoc analysis of data from the International Infant Hydrocephalus Study (IIHS)-a prospective, multicenter study of infants (< 24 months old) with hydrocephalus from aqueductal stenosis who were treated with either an ETV or shunt. During various stages of a 5-year follow-up period, the following craniometrics were measured: HC, HC centile, HCz-score, and frontal-occipital horn ratio (FOR). Data were compared in an analysis of covariance, adjusting for baseline variables including age at surgery and sex. Results Of 158 enrolled patients, 115 underwent an ETV, while 43 received a shunt. Both procedures led to improvements in the mean HC centile position andz-score, a trend which continued until the 5-year assessment point. A similar trend was noted for FOR which was measured at 12 months and 3 years following initial treatment. Although the values were consistently higher for ETV compared with shunt, the differences in HC value, centile, andz-score were not significant. ETV was associated with a significantly higher FOR compared with shunting at 12 months (0.52 vs 0.44;p = 0.002) and 3 years (0.46 vs 0.38;p = 0.03) of follow-up. Conclusion ETV and shunting led to improvements in HC centile,z-score, and FOR measurements during long-term follow-up of infants with hydrocephalus secondary to aqueductal stenosis. Head size did not significantly differ between the treatment groups during follow-up, however ventricle size was greater in those undergoing ETV when measured at 1 and 3 years following treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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