The prognostic value of monosomal karyotype (MK) in higher-risk patients with myelodysplastic syndromes treated with 5-Azacitidine: A retrospective analysis of the Hellenic (Greek) Myelodysplastic syndromes Study Group

Autor:	Papageorgiou, S.G. Vasilatou, D. Kontos, C.K. Kotsianidis, I. Symeonidis, A. Galanopoulos, A.G. Hatzimichael, E. Megalakaki, A. Poulakidas, E. Diamantopoulos, P. Vassilakopoulos, T.P. Zikos, P. Papadaki, H. Mparmparousi, D. Bouronikou, E. Panayiotidis, P. Viniou, N.-A. Pappa, V.
Jazyk:	angličtina
Rok vydání:	2018
Popis:	In this study, we investigated the incidence and prognostic impact of monosomal karyotype (MK) in 405 higher-risk Myelodysplastic Syndromes (MDS) patients treated with 5-AZA. The MK was present in 66 out of 405 (16.3%) patients, most of whom had complex karyotype (CK). MK was strongly associated with CK and the cytogenetic risk defined according to IPSS-R, as well as with high-risk disease, according to IPSS (P =.029), IPSS-R (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______2127::8c977081807354576443849bb9bd354f https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107292 Zobrazit plný text záznamu