| Autor: |
Tampakis, A. Tampaki, E.C. Nonni, A. Tsourouflis, G. Posabella, A. Patsouris, E. Kontzoglou, K. von Flüe, M. Nikiteas, N. Kouraklis, G. |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Popis: |
Background: Metastatic disease in colorectal cancer represents a major cause of significant cancer-associated morbidity and mortality. L1CAM is a stem cell marker, cell adhesion molecule, belongs to the immunoglobulin superfamily of cell adhesion molecules (IgCAM) and it is aberrantly expressed in several different types of human solid tumors. The aim of the present study was to assess the expression patterns of L1CAM and its clinical significance in colorectal cancer. Patients and methods: Surgical specimens of 109 patients with primary resectable colorectal cancer were examined for L1CAM expression via immunohistochemistry and the results were correlated with clinical and survival data. Results: L1CAM expression was significantly correlated with advanced stage of disease (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
