| Autor: |
Meyer, L. Bechstein, M. Bester, M. Hanning, U. Brekenfeld, C. Flottmann, F. Kniep, H. Van Horn, N. Deb-Chatterji, M. Thomalla, G. Sporns, P. Yeo, L.L.-L. Tan, B.Y.-Q. Gopinathan, A. Kastrup, A. Politi, M. Papanagiotou, P. Kemmling, A. Fiehler, J. Broocks, G. |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Popis: |
Background and Purpose: This study evaluates the benefit of endovascular treatment (EVT) for patients with extensive baseline stroke compared with best medical treatment. Methods: This retrospective, multicenter study compares EVT and best medical treatment for computed tomography (CT)-based selection of patients with extensive baseline infarcts (Alberta Stroke Program Early CT Score ≤5) attributed to anterior circulation stroke. Patients were selected from the German Stroke Registry and 3 tertiary stroke centers. Primary functional end points were rates of good (modified Rankin Scale score of ≤3) and very poor outcome (modified Rankin Scale score of ≥5) at 90 days. Secondary safety end point was the occurrence of symptomatic intracerebral hemorrhage. Angiographic outcome was evaluated with the modified Thrombolysis in Cerebral Infarction Scale. Results: After 1:1 pair matching, a total of 248 patients were compared by treatment arm. Good functional outcome was observed in 27.4% in the EVT group, and in 25% in the best medical treatment group (P=0.665). Advanced age (adjusted odds ratio, 1.08 [95% CI, 1.05-1.10], P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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