| Autor: |
Wang, Q. Afshin, A. Yakoob, M.Y. Singh, G.M. Rehm, C.D. Khatibzadeh, S. Micha, R. Shi, P. Mozaffarian, D. Ezzati, M. Fahimi, S. Wirojratana, P. Powles, J. Elmadfa, I. Rao, M. Alpert, W. Lim, S.S. Engell, R.E. Andrews, K.G. Abbott, P.A. Abdollahi, M. Abeyá Gilardon, E.O. Ahsan, H. Al Nsour, M.A.A. Al-Hooti, S.N. Arambepola, C. Fernando, D.N. Barennes, H. Barquera, S. Baylin, A. Becker, W. Bjerregaard, P. Bourne, L.T. Capanzana, M.V. Castetbon, K. Chang, H.-Y. Chen, Y. Cowan, M.J. Riley, L.M. De Henauw, S. Ding, E.L. Duante, C.A. Duran, P. Barbieri, H.E. Farzadfar, F. Hadziomeragic, A.F. Fisberg, R.M. Forsyth, S. Garriguet, D. Gaspoz, J.-M. Gauci, D. Calleja, N. Ginnela, B.N.V. Guessous, I. Gulliford, M.C. Hadden, W. Haerpfer, C. Hoffman, D.J. Houshiar-Rad, A. Huybrechts, I. Hwalla, N.C. Ibrahim, H.M. Inoue, M. Jackson, M.D. Johansson, L. Keinan-Boker, L. Kim, C.-I. Koksal, E. Lee, H.-J. Li, Y. Lipoeto, N.I. Ma, G. Mangialavori, G.L. Matsumura, Y. McGarvey, S.T. Fen, C.M. Monge-Rojas, R.A. Musaiger, A.O. Nagalla, B. Naska, A. Ocke, M.C. Oltarzewski, M. Szponar, L. Orfanos, P. Ovaskainen, M.-L. Tapanainen, H. Pan, W.-H. Panagiotakos, D.B. Pekcan, G.A. Petrova, S. Piaseu, N. Pitsavos, C. Posada, L.G. Sánchez-Romero, L.M. Selamat, R.B.T. Sharma, S. Sibai, A.M. Sichieri, R. Simmala, C. Steingrimsdottir, L. Swan, G. Sygnowska, E.H. Templeton, R. Thanopoulou, A. Thorgeirsdóttir, H. Thorsdottir, I. Trichopoulou, A. Tsugane, S. Turrini, A. Vaask, S. van Oosterhout, C. Veerman, J.L. Verena, N. Waskiewicz, A. Zaghloul, S. Zajkás, G. |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Popis: |
Background: Saturated fat (SFA), x-6 (n-6) polyunsaturated fat (PUFA), and trans fat (TFA) influence risk of coronary heart disease (CHD), but attributable CHD mortalities by country, age, sex, and time are unclear. Methods and Results: National intakes of SFA, n-6 PUFA, and TFA were estimated using a Bayesian hierarchical model based on country-specific dietary surveys; food availability data; and, for TFA, industry reports on fats/oils and packaged foods. Etiologic effects of dietary fats on CHD mortality were derived from meta-analyses of prospective cohorts and CHD mortality rates from the 2010 Global Burden of Diseases study. Absolute and proportional attributable CHD mortality were computed using a comparative risk assessment framework. In 2010, nonoptimal intakes of n-6 PUFA, SFA, and TFA were estimated to result in 711 800 (95% uncertainty interval [UI] 680 700-745 000), 250 900 (95% UI 236 900-265 800), and 537 200 (95% UI 517 600-557 000) CHD deaths per year worldwide, accounting for 10.3% (95% UI 9.9%-10.6%), 3.6%, (95% UI 3.5%-3.6%) and 7.7% (95% UI 7.6%-7.9%) of global CHD mortality. Tropical oil-consuming countries were estimated to have the highest proportional n-6 PUFA- and SFAattributable CHD mortality, whereas Egypt, Pakistan, and Canada were estimated to have the highest proportional TFA-attributable CHD mortality. From 1990 to 2010 globally, the estimated proportional CHD mortality decreased by 9% for insufficient n-6 PUFA and by 21% for higher SFA, whereas it increased by 4% for higher TFA, with the latter driven by increases in low- and middle-income countries. Conclusions: Nonoptimal intakes of n-6 PUFA, TFA, and SFA each contribute to significant estimated CHD mortality, with important heterogeneity across countries that informs nation-specific clinical, public health, and policy priorities. © 2016 The Authors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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