| Autor: |
Chadio, S. Kotsampasi, B. Taka, S. Liandris, E. Papadopoulos, N. Plakokefalos, E. |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Popis: |
The aim of this study was to characterise the effects of maternal undernutrition during gestation on hepatic gluconeogenic enzyme gene expression and to determine whether such effects are mediated through epigenetic changes in the glucocorticoid receptor (GR). Pregnant ewes were fed a 50% nutrient-restricted diet from Day 0 to 30 (R1) or from Day 31 to 100 of gestation (R2) or a 100% diet throughout gestation (Control). After parturition lambs were fed to appetite. At 10 months of age offspring were euthanised and livers were removed. Maternal undernutrition did not affect offspring bodyweight at birth or at 10 months of age. However, liver weight of males of the R2 group was lower (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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