| Autor: |
Rovina, N. Hillas, G. Dima, E. Vlastos, F. Loukides, S. Veldekis, D. Roussos, C. Alhanatis, M. Bakakos, P. |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
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| Popis: |
Cytokines are key players in the biological processes of malignant tumors and special interest has been focused on cytokines exerting tumor and anti-tumor properties, such as vascular endothelial growth factor (VEGF) and Interleukin-18 (IL-18). Aim of this study was to assess IL-18 and VEGF levels in induced sputum of lung cancer patients at diagnosis, and assess their possible association with the histological type of cancer, the stage and the overall patient survival.Seventy six patients with a diagnosis of lung cancer were recruited and were followed up for 48. months. Thirteen healthy smokers and 16 healthy non-smokers were used as control groups. VEGF and IL-18 were measured by ELISA in sputum supernatants at the time of diagnosis. Lung cancer patients had significantly higher baseline IL-18 and VEGF levels compared to healthy controls (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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