| Autor: |
Markaki, S Protopapas, A Milingos, S Lazaris, D and Antsaklis, A Michalas, S |
| Jazyk: |
angličtina |
| Rok vydání: |
2005 |
| Popis: |
Background. Primary peritoneal mesothelioma is regarded as a fatal disease that presents with progressive ascites at a relatively late stage of its natural history. Differential diagnosis between this rare tumor and both serous papillary carcinoma of the peritoneum and ovary can be problematic. Case. A 54-year-old woman presented to our institution with a 4-month history of dull epigastric pain and increased abdominal girth. Exploratory laparotomy revealed the presence of extensive intraperitoneal dissemination of a malignant neoplasm without a recognizable primary site. Suboptimal cytoreduction was carried out, and histological diagnosis was that of a malignant epithelioid mesothelioma. This was confirmed with a panel of immunohistochemical markers. The patient despite having a complete response after adjuvant chemotherapy died 18 months after primary surgery. Conclusion. No single immunohistochemical stain is pathognomonic of peritoneal primary malignant mesothelioma (PMM), and the results of a panel of antibodies should be interpreted to set the diagnosis. (c) 2004 Published by Elsevier Inc. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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