Soluble urokinase plasminogen activator receptor informs on the progression course after multiple injuries

Autor:	Patrani, M. Tsaganos, T. Kotzampassi, K. Paraschos, M. Katsenos, C. Giamarellos-Bourboulis, E.J. Mandragos, K.
Jazyk:	angličtina
Rok vydání:	2016
Popis:	Purpose: The purpose of this study is to study the use of soluble urokinase plasminogen activator receptor (suPAR) for the prognosis of multiple organ dysfunction (MOF) after multiple traumas. Methods: Serum suPAR was measured within the first 24 h after multiple injuries in 85 patients. Measurements were repeated after 4 d or at sepsis onset. Results: Odds ratio for trauma-associated MOF was 4.09 (p: 0.026) with admission suPAR greater than 8 ng/ml. More than 40% increases of suPAR were associated with odds ratio 9.33 (p: 0.047) for severe sepsis. Conclusions: suPAR is a useful surrogate biomarker for development of MOF and severe sepsis after multiple traumas. © 2016 Informa UK Limited, trading as Taylor & Francis Group.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______2127::61bed5dea91c9608c051120811cf9235 https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3005753 Zobrazit plný text záznamu