| Autor: |
Deftereos, Spyridon Giannopoulos, Georgios Kossyvakis, Charalampos Kaoukis, Andreas Raisakis, Konstantinos and Panagopoulou, Vasiliki Miliou, Antigoni Theodorakis, Andreas and Driva, Metaxia Pyrgakis, Vlasios Stefanadis, Christodoulos and Cleman, Michael W. |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Popis: |
Background Evidence shows that the soluble tumour necrosis factor-related apoptosis-inducing ligand (sTRAIL) may play a protective role against atherosclerosis. This study sought to investigate the potential association of sTRAIL levels with intravascular ultrasound (IVUS) and virtual histology characteristics of coronary plaques. Methods Patients with stable angina or positive for ischaemia non-invasive test were submitted to left cardiac catheterisation. Coronary blood samples were collected and sTRAIL was measured. Coronary arteries with at least one 50% or greater stenosis were studied with IVUS. Results 56 coronary arteries were studied with significant coronary artery disease. Plaque volume per unit of arterial length was 63 +/- 65 mm(3)/cm in arteries at the lower quartile of sTRAIL concentration versus 30 +/- 64 mm(3)/cm at the upper quartile (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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