| Autor: |
Nicolaides, Nicolas C. Lamprokostopoulou, Agaristi Polyzos, Alexandros Kino, Tomoshige Katsantoni, Eleni Triantafyllou, Panagiota Christophoridis, Athanasios Katzos, George and Dracopoulou, Maria Sertedaki, Amalia Chrousos, George P. and Charmandari, Evangelia |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Popis: |
Background Transient generalized glucocorticoid hypersensitivity is a rare disorder characterized by increased tissue sensitivity to glucocorticoids and compensatory hypo-activation of the hypothalamic-pituitary-adrenal axis. The condition itself and the underlying molecular mechanisms have not been elucidated. Objective To present the clinical manifestations, endocrinologic evaluation and transcriptomic profile in a patient with transient generalized glucocorticoid hypersensitivity. Design and Results A 9-year-old girl presented with an 8-month history of clinical manifestations suggestive of Cushing syndrome. Endocrinologic evaluation revealed undetectable 08: 00 h ACTH ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
