| Autor: |
RABKIN, CS HILGARTNER, MW HEDBERG, KW ALEDORT, LM and HATZAKIS, A EICHINGER, S EYSTER, ME WHITE, GC KESSLER, CM LEDERMAN, MM DEMOERLOOSE, P BRAY, GL COHEN, AR and ANDES, WA MANCOJOHNSON, M SCHRAMM, W KRONER, BL and BLATTNER, WA GOEDERT, JJ |
| Jazyk: |
angličtina |
| Rok vydání: |
1992 |
| Předmět: |
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| Popis: |
Objective. - To determine the types and rates of cancers occurring in excess in the presence of infection with the human immunodeficiency virus type 1 (HIV-1). Design. - Cohort analytic study of HIV-infected and HIV-uninfected subjects followed for up to 12 years. Setting. - Fifteen hemophilia treatment centers. Patients. - A total of 1701 patients with hemophilia, of whom 1065 (63%) were HIV-1 seropositive. Main Outcome Measures. -Morphologic classification and incidence rates of cancers. Main Results. - The incidence of non-Hodgkin’s lymphoma after HIV seroconversion averaged 0.15 case per 100 person-years (95% confidence interval [Cl], 0.08 to 0.25) and rose exponentially with increasing duration of HIV infection. Although the greatest absolute risk of lymphoma was in the oldest age group, the relative increase compared with general population rates was 38-fold in subjects 10 to 39 years old and 12-fold in older subjects (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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