Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) study

Autor: Teerlink, J.R. Metra, M. Filippatos, G.S. Davison, B.A. Bartunek, J. Terzic, A. Gersh, B.J. Povsic, T.J. Henry, T.D. Alexandre, B. Homsy, C. Edwards, C. Seron, A. Wijns, W. Cotter, G. for the CHART Investigators
Jazyk: angličtina
Rok vydání: 2017
Popis: Aims: Left ventricular (LV) reverse remodelling is an important marker of improved outcomes in patients with advanced heart failure (HF). We examined the impact of the intramyocardial administration of bone-marrow-derived, lineage-directed, autologous cardiopoietic mesenchymal stem cells (C3BS-CQR-1) on LV remodelling in patients with advanced HF enrolled in the CHART-1 study. Methods and results: Patients (n=351) with symptomatic advanced HF secondary to ischaemic heart disease, and reduced LV ejection fraction (LVEF
Databáze: OpenAIRE