High-resolution NMR spectroscopy of the β-amyloid(1-28) fibril typical for Alzheimer's disease
| Autor: | Mikros, E. Benaki, D. Humpfer, E. Spraul, M. Loukas, S. Stassinopoulou, C.I. Pelecanou, M. |
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| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Popis: | Unlabeled samples of the β-amyloid peptide(1-28) fibrils typical of Alzheimer's disease could be used to obtain well-resolved one- and two-dimensional 1H NMR spectra (see picture). The technique applied was high-resolution magic-angle spinning on a 600 MHz NMR spectrometer. The results are in agreement with a parallel, in-register arrangement of the β-amyloid peptide in the fibril. |
| Databáze: | OpenAIRE |
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