| Autor: |
Anker, S.D. Siddiqi, T.J. Filippatos, G. Zannad, F. Ferreira, J.P. Pocock, S.J. Brueckmann, M. Zeller, C. Packer, M. Butler, J. |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Popis: |
Aims: To report data from EMPEROR-Preserved according to prespecified endpoints of DELIVER. Methods and results: In order to assess the impact of DELIVER-like definition on EMPEROR-Preserved outcomes, the following differences were reconciled: (1) the primary outcome in DELIVER added urgent heart failure (HF) visits to cardiovascular death or HF hospitalizations; (2) the EMPEROR-Preserved trial did not require documentation of physical findings or laboratory tests for confirming a HF hospitalization and it included events of 12–24 h if intensification of treatment was not only oral diuretics; (3) DELIVER excluded undetermined causes of deaths from the primary endpoint; (4) the composite renal endpoint in DELIVER included a sustained ≥50% decline in estimated glomerular filtration rate and incorporated renal death; and (5) DELIVER will assess outcomes in the overall population and in patients with ejection fraction (EF) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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