Richter's transformation as leptomeningeal infiltration in a chronic lymphocytic leukemia patient receiving venetoclax. Could blood-brain barrier be a disease 'sanctuary' during venetoclax treatment?

Autor: Dimou, M. Bitsani, A. Roumelioti, M. Dimitrakopoulou, A. Iliakis, T. Pardalis, V. Grafakos, I. Kalyva, S. Markopoulos, A. Kyrtsonis, M.-C. Panayiotidis, P.
Jazyk: angličtina
Rok vydání: 2021
Popis: Our unique case of Richter's Transformation presenting as leptomeningial infiltration in a CLL patient receiving venetoclax raises questions on whether the drug penetrates the blood-brain barrier and at what extend, especially in reduced doses given for drug-drug interactions. © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Databáze: OpenAIRE