Global survey of the frequency of atrial fibrillation–associated stroke

Autor: Perera, Kanjana S., Vanassche, Thomas, Bosch, Jackie, Swaminathan, Balakumar, Mundl, Hardi, Giruparajah, Mohana, Barboza, Miguel A., O’Donnell, Martin J., Gomez-Schneider, Maia, Hankey, Graeme J., Yoon, Byung-Woo, Roxas, Artemio, Lavallee, Philippa, Sargento-Freitas, Joao, Shamalov, Nikolay, Brouns, Raf, Gagliardi, Rubens J., Kasner, Scott E., Pieroni, Alessio, Vermehren, Philipp, Kitagawa, Kazuo, Wang, Yongjun, Muir, Keith, Coutinho, Jonathan M., Connolly, Stuart J., Hart, Robert G., Czeto, K., Kahn, M., Mattina, K.R., Ameriso, S.F., Pujol-Lereis, V., Hawkes, M., Pertierra, L., Perera, N., De Smedt, A., Van Dyck, R., Van Hooff, R.J., Yperzeele, Laetitia, Gagliardi, V.D.B., Cerqueir, L.G., Yang, X., Chen, W., Amarenco, P., Guidoux, C., Ringleb, P.A., Bereczki, D., Vastagh, I., Canavan, M., Toni, D., Anzini, A., Colosimo, C., De Michele, M., Di Mascio, M.T., Durastanti, L., Falcou, A., Fausti, S., Mancini, A., Mizumo, S., Uchiyama, S., Kim, C.K., Jung, S., Kim, Y., Kim, J.A., Jo, J.Y., Arauz, A., Quiroz-Compean, A., Colin, J., Nederkoorn, P.J., Marianito, V.P., Cunha, L., Santo, G., Silva, F., Coelho, J., Kustova, M., Meshkova, K., Williams, G., Siegler, J., Zhang, C., Gallatti, N., Kruszewski, M.
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Stroke: a journal of cerebral circulation
ISSN: 0039-2499
Popis: Background and Purpose— Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features. Methods— Consecutive patients hospitalized for ischemic stroke in 2013 to 2014 were surveyed from 19 stroke research centers in 19 different countries. Data were analyzed by global regions and World Bank income levels. Results— Of 2144 patients with ischemic stroke, 590 (28%; 95% confidence interval, 25.6–29.5) had AF-associated stroke, with highest frequencies in North America (35%) and Europe (33%) and lowest in Latin America (17%). Most had a history of AF before stroke (15%) or newly detected AF on electrocardiography (10%); only 2% of patients with ischemic stroke had unsuspected AF detected by poststroke cardiac rhythm monitoring. The mean age and 30-day mortality rate of patients with AF-associated stroke (75 years; SD, 11.5 years; 10%; 95% confidence interval, 7.6–12.6, respectively) were substantially higher than those of patients without AF (64 years; SD, 15.58 years; 4%; 95% confidence interval, 3.3–5.4; P75 years old) and more often women.
Databáze: OpenAIRE