| Autor: |
Norte, A.C., Heylen, D., Araújo, P.M., Pascoal da Silva, L., Sprong, H., Krawczyk, A., Costantini, D., Eens, M., Núncio, M.S., Ramos, J.A., Lopes de Carvalho, I. |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Popis: |
Borrelia burgdorferi sensu lato (s.l.) is a tick-borne zoonotic agent maintained in enzootic cycles in nature by vertebrate reservoir hosts, including mammals, lizards and birds. To understand the eco-epidemiology of Lyme borreliosis it is necessary to evaluate the relationships between Borrelia genospecies and vertebrate reservoir hosts. We surveyed Borrelia infection prevalence in avian hosts and using wild birds as models, we assessed the physiological impact of infection in reservoir hosts and how exposure to stress could affect hosts’ infectivity to vector ticks. This helps to understand how these host-parasite interactions may affect tick-borne zoonotic agents’ circulation and transmission, and, ultimately, disease risk. Thrushes (Turdus spp.) were the most important birds in the enzootic cycle of Borrelia. The diversity of Borrelia genospecies detected in ticks feeding on birds was high, and the most common genospecies was B. garinii, a pathogenic genospecies. The ubiquitous blackbird Turdus merula successfully transmitted B. turdi, B. valaisiana and B. burgdorferi s.s. to vector ticks in laboratory conditions. There was no evidence that exposure to stress increased infectivity of wild avian hosts to vector ticks in an experiment performed in captivity. However, oxidative balance (protein carbonyls and glutathione peroxidase levels) of naïve blackbirds was affected by experimental infection with Borrelia, suggesting that these bacteria may inflict non-negligible physiological harm on its natural reservoir hosts with potential impact on transmission success. N/A |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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