Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole Effet de la température et du propylène glycol comme cosolvant sur la dissolution du clotrimazole

Autor: Rahimpour, E., Zhao, H., Jouyban, A., Hanaee, J., POTURCU, Kader, Rezaei, H., Nemati, A.
Jazyk: angličtina
Rok vydání: 2022
Popis: © 2022 Académie Nationale de PharmacieHerein, the solubility study of clotrimazole was performed in a propylene glycol + water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol + water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol + water and fitted to the Jouyban-Acree equation.
Databáze: OpenAIRE