| Autor: |
Çömlekçi, Selçuk, Aksoy, Fatma Tutku, Uğuz, Abdülhadi Cihangir, Kumbul Doğuç, Duygu, Olgaç Dündar, Nihal, Yücel, Halime, Çelik, Ömer, Dündar, Bumin Nuri |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Popis: |
Background: Electromagnetic fields may primarily affect cognitive functions. It has notbeen elucidated how electromagnetic radiation affects the brain, particularly in theyoung age group. We aimed to examine the cognitive function, expression of N-methyl-D-aspartate receptors (NMDA), and EEG alterations in weaned rats exposed to a 2.45GHz electromagnetic field. Materials and Methods: Twenty-one weaned (21 days old)male Wistar Albino rats were divided into two groups as experimental group (n=12)and control group (n=9). Animals in the experimental group were exposed to a 2.45GHz electromagnetic field for one hour a day for more than 28 days. At the end of thisperiod, rats were subjected to training and learning test using Morris Water Maze.After obtaining EEG records, hippocampi were removed. 2A and 2B subunits of NMDAreceptors were studied in hippocampal homogenates using the Western Blot method.Results: There were no statistically significant differences between the two groups inmeasures of latency to target quadrant, time spent in the target quadrant, andaverage swim speed as compared in Morris water maze. However, the time to arriveat the visible platform was significantly longer in experimental animals. There were nostatistically significant differences in expression of 2A and 2B subunits of NMDAreceptors between the two groups. Evaluation of EEG records revealed that spikefrequency was significantly higher and time to first spike was significantly shorter inthe experimental group. Conclusion: These results indicated that a 2.45 GHzelectromagnetic field might negatively affect EEG, motivation, and attention,particularly in the young age group. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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