Thiols in a nitric oxide synthase-containing Nocardia sp. NRRL 5646
Autor: | Lee, Sungwon, Bergeron, Hélène, Lau, Peter C. K., Rosazza, John P. N. |
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Jazyk: | angličtina |
Rok vydání: | 2007 |
Předmět: | |
Popis: | Mycothiol (MSH) [1-D-myo-inosityl-2-(N-acetyl-L-cysteinyl)amido-2-deoxy-{alpha}-D-glucopyranoside], isolated as the bimane derivative, was established to be the major thiol in Nocardia sp. strain NRRL 5646, a species most closely related to Nocardia brasiliensis strain DSM 43758T. Thiol formation and detection of MSH-dependent formaldehyde dehydrogenase activity in cell extracts are relevant to the possible modulation of nitric oxide toxicity generated by strain NRRL 5646. |
Databáze: | OpenAIRE |
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