| Autor: |
Koy, Timmo, Ganse, Bergita, Rittweger, Jörn, Pohle-Fröhlich, Regina, Frings-Meuthen, Petra, Johannes, Bernd Wolfgang, Felsenberg, Dieter, Eysel, Peer, Bansmann, Martin, Belavy, Daniel Ludovic |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
Objectives: Spaceflight back pain and intervertebral disc (IVD) herniations cause problems in astronauts. Purpose of this study was to assess changes in T2-relaxation-time through MRI measurements before and after head-down tilt bed-rest, a spaceflight analog. Methods: 8 men participated in the bed-rest study. Subjects remained in 6° head down tilt bed-rest in two campaigns of 21 days, and received a nutritional intervention (potassium bicarbonate 90 mmol/d) in a cross-over design. MRI measurements were performed 2 days before bed-rest, as well as one and five days after getting up. Image Segmentation and data analysis were conducted for the IVDs Th12/L1 to L5/S1. Results: 7 subjects, average age of 27.6 (SD 3.3) years, completed the study. Results showed a significant increase in T2-time in all IVDs (p < 0.001), more pronounced in the nucleus pulposus than in the annulus fibrosus (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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