Multivendor fully automatic uncertainty management approaches for the intuitive representation of DME fluid accumulations in OCT images

Autor: Vidal, Plácido, Moura, Joaquim de, Novo Buján, Jorge, Ortega Hortas, Marcos
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Popis: [Abstract]: Diabetes represents one of the main causes of blindness in developed countries, caused by fluid accumulations in the retinal layers. The clinical literature defines the different types of diabetic macular edema (DME) as cystoid macular edema (CME), diffuse retinal thickening (DRT), and serous retinal detachment (SRD), each with its own clinical relevance. These fluid accumulations do not present defined borders that facilitate segmentational approaches (specially the DRT type, usually not taken into account by the state of the art for this reason) so a diffuse paradigm is used for its detection and visualization. In this paper, we propose three novel approaches for the representation and characterization of these types of DME. A baseline proposal, using a convolutional neural network as backbone, another based on transfer learning from a general domain, and a third approach exploiting information of regions without a defined label. Overall, our baseline proposal obtained an AUC of 0.9583 ± 0.0093, the approach pretrained with a general-domain dataset an AUC of 0.9603 ± 0.0087, and the approach pretrained in the domain taking advantage of uncertainty, an AUC of 0.9619 ± 0.0073. Ministerio de Ciencia e Innovación; RTI2018-095894-B-I00 Instituto de Salud Carlos III; DTS18/00136 Ministerio de Ciencia e Innovación; FPU18/02271 Ministerio de Ciencia e Innovación; PID2019-108435RB-I00 Xunta de Galicia; ED431C 2020/24 Xunta de Galicia; ED481B 2021/059 Axencia Galega de Innovación; IN845D 2020/38 Xunta de Galicia; ED431G 2019/01
Databáze: OpenAIRE