Autor: |
Koivusalo, Saila B., Rönö, Kristiina, Klemetti, Miira M., Roine, Risto P., Lindstrom, Jaana, Erkkola, Maijaliisa, Kaaja, Risto J., Pöyhönen-Alho, Maritta, Tiitinen, Aila, Huvinen, Emilia, Andersson, Sture, Laivuori, Hannele, Valkama, Anita Johanna, Meinila, Jelena, Kautiainen, Hannu, Eriksson, Johan G., Stach-Lempinen, Beata |
Přispěvatelé: |
Department of Obstetrics and Gynecology, Clinicum, Department of Food and Nutrition, Maijaliisa Erkkola / Principal Investigator, Children's Hospital, Institute for Molecular Medicine Finland, Pregnancy and Genes, Department of General Practice and Primary Health Care, Johan Eriksson / Principal Investigator, Department of Medical and Clinical Genetics, Medicum, Nutrition Science, HUS Gynecology and Obstetrics, Teachers' Academy, Family nutrition and wellbeing |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
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Popis: |
OBJECTIVE To assess whether gestational diabetes mellitus (GDM) can be prevented by a moderate lifestyle intervention in pregnant women who are at high risk for the disease. RESEARCH DESIGN AND METHODS Two hundred ninety-three women with a history of GDM and/or a prepregnancy BMI of >= 30 kg/m(2) were enrolled in the study at RESULTS A total of 269 women were included in the analyses. The incidence of GDM was 13.9% in the intervention group and 21.6% in the control group ([95% CI 0.40-0.98%]; P = 0.044, after adjustment for age, prepregnancy BMI, previous GDM status, and the number of weeks of gestation). Gestational weight gain was lower in the intervention group (20.58 kg [95% CI 21.12 to 20.04 kg]; adjusted P = 0.037). Women in the intervention group increased their leisure time physical activity more and improved their dietary quality compared with women in the control group. CONCLUSIONS A moderate individualized lifestyle intervention reduced the incidence of GDM by 39% in high-risk pregnant women. These findings may have major health consequences for both the mother and the child. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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