Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases
| Autor: | Laulajainen-Hongisto, Anu, Toppila-Salmi, Sanna Katriina, Luukkainen, Annika, Kern, Robert |
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| Přispěvatelé: | HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Clinicum, Helsinki University Hospital Area, University of Helsinki, HUS Inflammation Center, Department of Pathology, Department of Dermatology, Allergology and Venereology, Medicum |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
MUCOUS CELL METAPLASIA
chronic rhinosinusitis allergic rhinitis (AR) RHINOVIRUS INFECTION BARRIER DYSFUNCTION respiratory system asthma respiratory tract diseases DIFFERENTIAL EXPRESSION inflammation CIGARETTE-SMOKE PERIOSTIN EXPRESSION NASAL POLYPS 1182 Biochemistry cell and molecular biology PRIMARY CILIARY DYSKINESIA epithelium GENE-EXPRESSION |
| Popis: | Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the airways. This review links environmental factors to host epithelial immunity in airway diseases. Understanding altered homeostasis of the airway epithelium might provide important targets for diagnostics and therapy of chronic airway diseases. |
| Databáze: | OpenAIRE |
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