A Prospective Cohort Study with Historical Control to Determine the Effectiveness of Autologous Conditioned Plasma (ACP®) in the Non-operative Treatment of Acute Achilles Tendon Ruptures

Autor: Kaniki, Nicole Lynn
Rok vydání: 2011
Předmět:
Zdroj: Digitized Theses
Popis: The purpose of this study was to investigate isokinetic strength, quality of life, range of motion, and calf circumference for patients with acute Achilles tendon rupture treated non- operatively with accelerated functional rehabilitation with or without Autologous Conditioned Plasma (ACP®). We used a cohort of patients (n=34) from a published randomized trial to serve as our historical control group. We recruited 51 consecutive patients and administered two ACP® injections during the first four weeks post injury. The mean between groups difference in plantar flexion strength (injured/uninjured) at one year post injury was 2.9% (95% Cl -13.6 to 7.8), p = 0.6 and -0.3% (95% Cl -13.6 to 13.0), p = 1.0 at 30°/s and 607s respectively. All secondary outcomes were also not different. The addition of ACP to a non-operative treatment protocol with accelerated functional rehabilitation does not provide better outcomes at one year post Achilles tendon rupture.
Databáze: OpenAIRE