Whole-genome sequence analysis: Evidences for new osteocalcin isoforms in fish and tetrapods

Autor: Laizé, Vincent, Gavaia, Paulo J., S B Viegas, Carla, Cancela, Leonor
Jazyk: angličtina
Rok vydání: 2006
Popis: The evolution of calcified tissues is a defining feature in vertebrate evolution. Investigating evolution of proteins involved in tissue calcification should help elucidate how calcified tissues have evolved. Osteocalcin (OC) is a small calcium-binding protein accumulated exclusively in bone and teeth, whose function, although essential for tissue calcification, remains unclear. Until recently, only a single osteocalcin isoform had been described (OC I).
Databáze: OpenAIRE