Histologic analysis of the irradiated anal sphincter

Autor:	Da Silva, Giovanna M, Berho, Mariana, Wexner, Steven D, Efron, Jonathan, Weiss, Eric G, Nogueras, Juan J, Vernava, Anthony M (3rd), Connor, Jason T, Gervaz, Pascal
Jazyk:	angličtina
Rok vydání:	2003
Předmět:	Adult Male Analysis of Variance ddc:617 Middle Aged Fibrosis/etiology/pathology Radiotherapy Adjuvant/adverse effects/methods Proctocolectomy Restorative/methods Anal Canal/pathology/radiation effects Preoperative Care Rectal Neoplasms/pathology/radiotherapy/surgery Linear Models Humans Female Aged
Zdroj:	Diseases of the Colon and Rectum, Vol. 46, No 11 (2003) pp. 1492-7
ISSN:	0012-3706
Popis:	There is accumulating evidence, both quantitative and qualitative, that pelvic irradiation adversely affects anorectal function. However, histologic evidence of sphincter injury has not been demonstrated. This study was designed to perform histologic assessment of collagen deposition and nerve alteration in the internal anal sphincters of rectal cancer patients who underwent abdominoperineal resection after adjuvant chemoradiation therapy and to correlate the degree of histologic changes with the time interval between chemoradiotherapy and abdominoperineal resection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______1400::fc5d14f0c87bdc923c96ed2b5b2adf31 https://archive-ouverte.unige.ch/unige:45088 Zobrazit plný text záznamu Full text from SpringerLink