| Autor: |
Raoelison, Guy Emmanuel, Terreaux, Christian, Queiroz, Emerson Ferreira, Zsila, F., Simonyi, M., Antus, S., Randriantsoa, A., Hostettmann, Kurt |
| Jazyk: |
angličtina |
| Rok vydání: |
2001 |
| Předmět: |
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| Zdroj: |
Helvetica Chimica Acta, Vol. 84 (2001) pp. 3470-3476 |
| ISSN: |
0018-019X |
| Popis: |
The stem bark CH2Cl2 extract of Ravensara crassifolia showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum in a bioautographic TLC assay. Activity-guided fractionation afforded two new alpha -pyrones : (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one (1) and (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran-2-one (2). Their structures and absolute configurations were established by NMR spectroscopy, chemical methods, and CD spectroscopy. The antifungal activity against C. cucumerinum was determined for both compounds. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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