Short and stereoselective synthesis of α-methylene-β-hydroxy-γ-butyrolactone diastereomers : Structures revised by theoretical investigations
| Autor: | Díaz, Gaspar, Carvalho, Gláucia S., Soares, Flávia R. F., Alcântara, Antônio F. de C., Diaz, Marisa A. N. |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
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| Popis: | A short synthetic approach allowed the preparation, in two steps, of (3S,4R)- and (3R,4R)-2- methylene-3-hydroxy-4-(hydroxymethyl)-γ-butyrolactones from 2,3-O-(3-pentylidene)-D-glyceraldehyde, with overall yields of 32 % and 9 %, respectively. The structure of these γ-butyrolactones was revised by experimental and theoretical investigations. Colegio de Farmacéuticos de la Provincia de Buenos Aires |
| Databáze: | OpenAIRE |
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