First round of focused library for cholera toxin inhibitor search
| Autor: | Podlipnik, C, Velter, I, Marcou, G, Belvisi, L, Bernardi, A., LA FERLA, BARBARA, NICOTRA, FRANCESCO |
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| Přispěvatelé: | Podlipnik, C, Velter, I, LA FERLA, B, Marcou, G, Belvisi, L, Nicotra, F, Bernardi, A |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: | |
| Popis: | C-Galactosides have been used as scaffolds to design a library of non-hydrolysable inhibitors of cholera toxin (CT). Test elements from the library were synthesized and found to inhibit CT binding to an asialofetuin-coated SPR chip with micromolar affinity. Preliminary results are reported. © 2007 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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