CLINICAL FEATURES AND RENAL PROGNOSIS IN LUPUS NEPHRITIS PATIENTS UNDERGOING A REPEATED BIOPSY: RESULTS OF 103 RE-BIOPSIES IN 438 PATIENTS
Autor: | M. Gatto, F. Saccon, F. Radice, P. G. Vercelloni, R. A. Sinico, G. Frontini, V. Binda, P. Messa, F. Alberici, G. Moroni, A. Doria . |
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Přispěvatelé: | Gatto, M, Saccon, F, Radice, F, Vercelloni, P, Sinico, R, Frontini, G, Binda, V, Messa, P, Alberici, F, Moroni, G, Doria ., A |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Popis: | Background: Indications to repeat renal biopsy (RB) in lupus nephritis (LN) are not unanimously acknowledged. Objectives: To evaluate the renal outcome of patients with LN undergoing a second RB. Methods: We retrospectively analyzed prospectively collected data of patients with LN followed up in four Italian referral centres for systemic lupus eryhtematosus. Serological and clinical information were retrieved according to a shared database. RB were classified according to ISN/RPS 2003 classification; chronicity (CI) and activity indexes (AI) were defined according to Austin et al. The primary renal outcome was renal failure, defined as serum creatinine (SCr)>1.0mg/dL with eGFR |
Databáze: | OpenAIRE |
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